Download Advances in Virus Research by Kenneth M. Smith and Max A. Lauffer (Eds.) PDF

By Kenneth M. Smith and Max A. Lauffer (Eds.)

ISBN-10: 0120398117

ISBN-13: 9780120398119

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Intermcdiate values were obtained when lower dosages were uscd. 9% by the irradiation. Mundry (195713) has attacked the conclusions reached from these experiments because he has been able to demonstrate an increased frequency of variants when infectivity of virus preparations are reduced by dilution as well as by irradiation. The apparent increase of variant frequency upon dilution is attributed to a release of an inhibitory action known to occur between strains of a virus. He cautions, therefore, that the variant frequency found following a treatment which reduces infectivity should be properly compared with a virus preparation diluted to the same infectivity as that found in the treated preparation.

B. Treatment of Virus Particles in Vitro . . . C . Induced Mutation of Different Strains of TMV . . D. Direction of Induced Mutation . . . . IV. The TMV Genome . . . . . . V. TMV Mutants and the Genetic Code . . . . A. Evidence for a Nonoverlapping Code . . . B. Matching Coding Triplets to the Amino Acid Replacements VI. Discussion and Summary . . . . . References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

These comments are not made with the object of relegating classification to a nebulous futurc. We believe that the present experimental results are sufficient to suggest a general framework for classification of elongated viruses. With regard to the details we agree with Richard von Wettstein, who fifty years ago said, in effect: “We should consider that the systematic units are not units defined by nature, but that they are abstractions. ” ACKNOWLEDGMENT T h e authors are greatly indebted to Dr.

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