Download Alcohol and the Nervous System by Edith V. Sullivan, Adolf Pfefferbaum PDF

By Edith V. Sullivan, Adolf Pfefferbaum

ISBN-10: 0444626190

ISBN-13: 9780444626196

Alcohol is the main ordinary drug on the earth, but alcoholism continues to be a significant habit affecting approximately 20 million american citizens. Our present realizing of alcohol's impression on mind constitution and similar practical harm is being revolutionized by means of genetic learn, simple neuroscience, mind imaging technology, and systematic learn of cognitive, sensory, and motor talents. quantity a hundred twenty five of the instruction manual of scientific Neurology is a complete, in-depth treatise of reports on alcohol and the mind protecting the fundamental knowing of alcohol's influence at the imperative worried process, the analysis and therapy of alcoholism, and prospect for restoration. The chapters inside of could be of curiosity to medical neurologists, neuropsychologists, and researchers in all aspects and degrees of the neuroscience of alcohol and alcoholism.

  • The first concentrated reference particularly on alcohol and the brain
  • Details our present knowing of ways alcohol affects the critical frightened system
  • Covers scientific and social influence of alcohol abuse issues and the biomedical outcomes of alcohol abuse
  • Includes part on neuroimaging of neurochemical markers and mind function

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Extra resources for Alcohol and the Nervous System

Example text

3). An acute elevation in brain reward thresholds hedonic habituation (or tolerance), and the b-process was observed during repeated acute withdrawal from includes affective or hedonic withdrawal (abstinence). ethanol, bearing a striking resemblance to human NEUROCIRCUITRY OF ALCOHOL ADDICTION: SYNTHESIS FROM ANIMAL MODELS 37 Fig. 3. 05, compared with vehicle controls at given timepoint postinjection). The effect was significant at 6 hours, a time when blood alcohol levels had declined to virtually undetectable levels following this dose of ethanol.

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2012). Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies. Addict Biol 17: 108–120. Bottomly D, Walter NA, Hunter JE et al. (2011). Evaluating gene expression in C57BL/6 J and DBA/2 J mouse striatum using RNA-Seq and microarrays. PLoS One 6: e17820. Breese GR, Overstreet DH, Knapp DJ et al. (2005). Prior multiple ethanol withdrawals enhance stressinduced anxiety-like behavior: inhibition by CRF1- and benzodiazepine-receptor antagonists and a 5-HT1a-receptor agonist.

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